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What is the Purpose for Farxiga?

 Farxiga (dapagliflozin) is an oral medication primarily used to:   1. Manage Type 2 Diabetes    Mechanism: It’s an SGLT2 (sodium-glucose cotransporter-2) inhibitor. It works by blocking glucose reabsorption in the kidneys, causing excess sugar to be excreted in urine.     Effect:  Lowers blood sugar levels, reduces HbA1c, and promotes weight loss (typically 2–4 kg).   2. Protect Heart & Kidneys (Key Long-Term Benefits)      - Heart Failure      - Approved to reduce hospitalization and death in adults with heart failure (both with and without diabetes).        - Improves heart function and symptoms like fatigue/swelling.      Chronic Kidney Disease (CKD)      - Slows kidney damage progression and lowers risk of kidney failure/dialysis in diabetic and non-diabetic CKD patients.      Cardiovascular Protection:      - Reduces risk of hear...

What is the Purpose for Farxiga?

 Farxiga (dapagliflozin) is an oral medication primarily used to:   1. Manage Type 2 Diabetes    Mechanism: It’s an SGLT2 (sodium-glucose cotransporter-2) inhibitor. It works by blocking glucose reabsorption in the kidneys, causing excess sugar to be excreted in urine.     Effect:  Lowers blood sugar levels, reduces HbA1c, and promotes weight loss (typically 2–4 kg).   2. Protect Heart & Kidneys (Key Long-Term Benefits)      - Heart Failure      - Approved to reduce hospitalization and death in adults with heart failure (both with and without diabetes).        - Improves heart function and symptoms like fatigue/swelling.      Chronic Kidney Disease (CKD)      - Slows kidney damage progression and lowers risk of kidney failure/dialysis in diabetic and non-diabetic CKD patients.      Cardiovascular Protection:      - Reduces risk of hear...

Long-Term Effects of Metformin

 Metformin is generally considered safe for long-term use, but it can have several effects on the body over time. Here are some key long-term effects: Long-Term Effects of Metformin   1. Gastrointestinal Issues      - Some people experience nausea, diarrhea, or abdominal discomfort, though these often subside over time.   2. Vitamin B12 Deficiency      - Long-term use can reduce B12 absorption, leading to deficiency (fatigue, neuropathy, anemia). Regular monitoring and supplementation may be needed.   3. Lactic Acidosis (Rare but Serious)      - A very rare risk in people with kidney impairment or severe liver disease.   4. Possible Kidney Function Impact      - Metformin is cleared by the kidneys, so dosage may need adjustment in renal impairment (though it doesn’t directly harm kidneys).   5. Weight Stabilization or Mild Loss      - Often promotes modest weight loss or prevents wei...

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